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The PhenX Toolkit is a web-based catalog of high-priority measures related to complex diseases, phenotypic traits and environmental exposures. These measures were selected by working groups of experts using a consensus process. 〔Maiese, D.R., Hendershot, T.P., Strader, L.C., Wagener, D.K., Hammond, J.A., Huggins, W., Kwok, R.K., Hancock, D.B., Whitehead, N.S., Nettles, D.S., Pratt, J.G., Scott, M.S., Conway, K.P., Junkins, H.A., Ramos, E.M., Hamilton, C.M.(2013) PhenX—Establishing a consensus process to select common measures for collaborative research. ''RTI Press''〕 Use of PhenX measures facilitates combining data from a variety of studies, and makes it easy for investigators to expand a study design beyond the primary research focus. 〔 〕 〔 〕 The Toolkit is funded by the National Human Genome Research Institute (NHGRI) with additional support from the Office of Behavioral and Social Sciences Research ((OBSSR )), the National Institute on Drug Abuse (NIDA), the National Institute of Mental Health ((NIMH )) of the National Institutes of Health (NIH), and the NIH Office of Disease Prevention's ((ODP's )) Tobacco Regulatory Science Program ((TRSP )). The measures are made available to the scientific community at no cost. ==Objectives== For genome-wide association studies (GWAS) and other studies involving human subjects, the use of standard measures can facilitate cross-study analyses. 〔 〕 〔 〕 Such analyses compare independent findings to validate results or combine studies to increase sample size and statistical power. This increased power makes it possible to identify more subtle and complex associations such as gene-gene and gene-environment interactions. 〔 〕 〔 〕 〔 〕 〔 〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「PhenX Toolkit」の詳細全文を読む スポンサード リンク
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